Not everyone has the opportunity to pick up and move to a new place. But, if you find yourself with that opportunity you should absolutely do it. Based on my own experience, it's the best thing ever.

Here are a few reasons why:

It's scary as fuck. This is 100% true but in the best possible way. I packed up everything and moved to Seattle. A city I have never stepped foot in because I thought the opportunity would lead to greener pastures. I was right. I now live in the best city in the world (3 months a year at least).
ROAD TRIP! If you're gonna do it, make it a road trip. I did it alone, but I had a fascinating book on tape that kept me entertained for the 4 days I was driving. I was able to go to beautiful places and meet beautiful people. To this very day, Bozeman Montana holds a special place in my heart because of the 15 hours I spent there.
Different is good. As humans, it's really easy for us to get set in our ways. Get up at the same time, drink the same coffee, drive the same car to the same place. It's comfortable, easy, and safe. Moving across the country will mess up that routine in a very dramatic yet fun way. You'll have to learn all new streets, new restaurants, and bars, new grocery store layouts. And while that sounds daunting, I promise it's actually quite fun.
You'll find out who you really are. This. This right here is the most important reason. When you do this you are absolutely betting on yourself. It's a very rare that you get to actually see what you're really made of. Do you become more inward and driven? Do you step out of your comfort zone and shine? Do you learn a new hobby? Do you become a new person? Yes to all those. Or not. I don't know you. You're just reading this goofy thing on my website.

I could go on and on about the benefits of moving, but 4 seems like a good enough number for now. Maybe I'll come back and add to it. Maybe I won't.